Peak Bio is a newly created venture out of the San Francisco Bay Area that will soon reach a critical milestone in our history of going public on NASDAQ. We are seeking scientific and business talent at two of our critical sites that include our center of research excellence in Palo Alto, California and our G&A infrastructure in South Florida.
Peak Bio is a clinical-stage biopharmaceutical company focused on commercializing innovative therapeutics that aim to improve and address significant unmet medical needs for patients with inflammatory, rare and specialty diseases and cancer. We seek qualified, energetic, and talented individuals with a desire for growth, and advancement but with a knack for working in a cross-cultural, team-based environment. The talent we seek works well with others and knows that, in the end, the company’s overarching goal is to improve the human health experience and help solve the medical mysteries that challenge us daily. As a company we will continue to explore, work closely with and partner with external researchers, clinicians, patient advocacy groups, academic institutions, governmental agencies, and our investors to continue to expand treatment options and partnerships to meet those expectations and find novel approaches to treat disease.
This is a full-time position based in our Palo Alto, California offices, and will initially report to the Head of Oncology.
This role will be important in driving the future of our business, demonstrating the ability to work scientifically with a unique business model, working collaboratively amongst other talented scientists who utilize expertise, analytics, creativity, and ingenuity to succeed.
Key Responsibilities
Produce tumor biology, xenografts- cell-line derived or PDx
Construct Immuno-oncology, syngeneic models
Produce FFPE Immunohistochemistry (IHC) and Microscopy
Extract tumor/ tissue DNA/ RNA and NGS/ RNAseq transcriptome analysis
Produce in vitro pharmacology and translation studies
Perform flow cytometry
Maintain cell culture
Perform data analysis and interpretation using standard methods and software (for e.g., Prism, Excel, FloJo, Basespace, Galaxy etc.)
Work with SDS-PAGE, Western Blotting and ELISA as needed
Work with transfection of cell lines and selection of stable clones as needed
Create novel engineered cancer cell lines as needed
Desired Abilities and Qualifications
MS in cell biology, tumor biology, immunology, or related with 4+ years or PhD with 1+ year of relevant industry experience
Experience with Potency screening- single agent and chemotherapy combination
Experience in In vitro pharmacology/ Tumor biology- Performed Dose selection and optimization experiments in cell line xenograft and/or PDX models in oncology setting.
Experience in pharmacokinetics- ELISAs for detection of antibodies in serum, AUC analysis.
Analysis of mechanism of action by immune cell profiling, or immunofluorescence and/or IHC.
Analysis of mechanism of action in cells/ tumor by qRT-PCR, SDS-PAGE, and RNAseq. Cell profiling/ lineage tracking by PCR or gene expression signatures.
Excellent documentation and organizational skills
Excellent interpersonal/communication skills in embodying a collaborative, respectful, courteous, capable company culture
What you will enjoy while working with us
(Any or all of these benefits are subject to change at any time at Peak Bio’s discretion).
Competitive Pay
Bonus Eligibility
Stock Option Eligibility
Health Care Plan
Medical
Dental
Vision
401(k) Plan
Family Leave (Maternity, Paternity)
Life Insurance
Long- and Short-Term Disability
Generous PTO Policy
Paid Company Holidays
Does Peak Bio’s mission and unique business model ignite your passion and interest? Does the opportunity to work alongside talented and welcoming team members make you want to join? Do the responsibilities and qualifications translate very similarly to what you have to offer? Does
the overall benefits package make you feel valued and appreciated? If you answer “yes” to these questions, we definitely want you to apply using the following link.
Job candidates should be aware that full vaccination against COVID-19 is required as a condition of employment subject to legally required exceptions. Peak Bio is an equal opportunity employer and encourages potential or current employees to request a reasonable accommodation under federal, state and local regulations, should one be needed.
Thank you for your interest!
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