Peak Bio is a newly created venture out of the San Francisco Bay Area that will soon reach a critical milestone in our history of going public on NASDAQ. We are seeking scientific and business talent at two of our critical sites that include our center of research excellence in Palo Alto, California and our G&A infrastructure in South Florida.
Peak Bio is a clinical-stage biopharmaceutical company focused on commercializing innovative therapeutics that aim to improve and address significant unmet medical needs for patients with inflammatory, rare and specialty diseases and cancer. We seek qualified, energetic, and talented individuals with a desire for growth, and advancement but with a knack for working in a cross-cultural, team-based environment. The talent we seek works well with others and knows that, in the end, the company’s overarching goal is to improve the human health experience and help solve the medical mysteries that challenge us daily. As a company we will continue to explore, work closely with and partner with external researchers, clinicians, patient advocacy groups, academic institutions, governmental agencies, and our investors to continue to expand treatment options and partnerships to meet those expectations and find novel approaches to treat disease.
This is a full-time position based in our Palo Alto, California offices, and will initially report to the Head of Oncology.
This role will be important in driving the future of our business, demonstrating the ability to work scientifically with a unique business model, working collaboratively amongst other talented scientists who utilize expertise, analytics, creativity and ingenuity to succeed.
Perform PCR and molecular cloning of antibody and His or Fc-tagged target protein extracellular domain (ECD) constructs
Perform plasmid purification and screening of recombinants
Maintain cell culture
Produce protein characterization (affinity determination, competitive binding assays, epitope determination) by plate-based methods (ELISA)
Construct SDS-PAGE and Western Blotting
Implement transfection of CHO cells and transient pool/ stable clonal analysis of antibody production as well as generation of stable engineered cell lines and expression analysis
Perform flow cytometry
Perform in vitro potency assays and/or antibody-related binding/internalization assays
Perform cell-based assays per SOP/ investigator guidance
Desired Abilities and Qualifications
BS in molecular biology, cell biology or related science with 4+ years of relevant industry experience or MS in above disciplines with 2+ years of relevant industry experience.
Performs well in a highly matrixed environment
Collaborative presence, working closely with-
antibody engineering team, generating recombinant antibodies by molecular cloning
antibody engineering team, screening for antibodies or plasma/hybridoma cells of interest
target validation team, identifying antibodies with desired properties
target validation team, performing cell-based assays per SOP
target validation team, qualifying their cell-based assays by SDS-PAGE
protein production team, identifying high producer clones
translation team, investigating MoA by SDS-PAGE
Excellent documentation and organizational skills
Excellent interpersonal/communication skills in embodying a collaborative, respectful, courteous, capable company culture
Experience with antibody-drug-conjugates (ADC) a plus.
Experience with transient mammalian (CHO and HEK) antibody or other protein expression a plus
What you will enjoy while working with us
(Any or all of these benefits are subject to change at any time at Peak Bio’s discretion).
Stock Option Eligibility
Health Care Plan
Family Leave (Maternity, Paternity)
Long- and Short- Term Disability
Generous PTO Policy
Paid Company Holidays
Does Peak Bio’s mission and unique business model ignite your passion and interest? Does the opportunity to work alongside talented and welcoming team members make you want to join? Do the responsibilities and qualifications translate very similarly to what you have to offer? Does the overall benefits package make you feel valued and appreciated? If you answer “yes” to these questions, we definitely want you to apply.
Job candidates should be aware that full vaccination against COVID-19 is required as a condition of employment subject to legally required exceptions. Peak Bio is an equal opportunity employer and encourages potential or current employees to request a reasonable accommodation under federal, state and local regulations, should one be needed.
Thank you for your interest!